At the roundabout which you will find immediately after the motorway exit, turn left and follow the signs for BIZZARRONE-CONFINE ITALIA/SVIZZERA (Italian/Switzerland border). Continue for approximately 12Km.
Immediately after a big shopping-centre called Bennet on the left; you will find a big roundabout crossed by the Varese-Como road SS342 (direction to Varese if you take the left, direction to Como on the right). Drive all around the roundabout for 360° and take again the road you have come from. Go straight on for approximately 50 meters and take a narrow road on the right (Via Marconi). After about 500 meters turn left into Via Grandi.
After 100 meters you will find Sisme on the left.